Endocrine Abstracts

Background and aim: There is an increasing use of computed tomography (CT) scans with an iodine-based contrast medium. Last year, a large University Hospital in Denmark performed 50 000 CT scans where each injection contained between 3500 and 7000 μg free iodine corresponding to 23–45 times normal daily intake. We wished to investigate if patients with newly diagnosed hyperthyroidism had been exposed to an iodine based CT scan within 1 year prior to symptoms of hyper...

Background and aim: Low T3 syndrome is associated with a poor prognosis in patients with chronic heart failure (CHF). It is controversial whether T3 treatment is indicated in CHF. A previous study using intravenous infusion of T3 for 72 h suggested a beneficial effect on cardiac performance.We aimed to evaluate the effect of 13 weeks of T3 treatment in patients with stable CHF on left ventricular ejection fraction (LVEF) compared to placebo.<p class=...

Aims: Diabetic patients with heart failure (HF) have an adverse prognosis, which could be linked with reduced left ventricular (LV) contractile reserve. Galectin-3 (Gal-3) and fibulin-1 are potential biomarkers of fibrosis. The aims were to evaluate the impact of DM on Gal-3 and fibulin-1 levels and the association to LV contractile reserve in HF patients with and without diabetes (DM).Methods and results: From an out-patient HF clinic 155 patients with ...